Welcome to the Abraham Lab!
We use methods in molecular virology and structural biology to study how viruses interact with cellular receptors and how neutralizing antibodies can block these interactions. We also investigate how viral polymerases replicate or transcribe viral genomes once viruses infect cells.
We focus this work on viruses that cause lethal human diseases with limited treatment or vaccine options.
Read our most recent publication, “Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.”
Check out our recent paper, “Structural basis for VLDLR recognition by eastern equine encephalitis virus.”
Read our recent paper, “Shifts in receptors during submergence of an encephalitic arbovirus.”
Check out our preprint on bioRxiv, “Structural and functional analysis of the Nipah virus polymerase complex.”
