We study how viruses interact with cellular receptors and how neutralizing antibodies can block these interactions. We focus on viruses that cause lethal human diseases with limited treatment or vaccine options.

Read ourĀ Nature paper, “VLDLR and ApoER2 are receptors for multiple alphaviruses” and the associated Nature News & Views.

Read ourĀ Science paper: “Structural basis for continued antibody evasion of the SARS-CoV-2 receptor-binding domain” and the associated press release, “This virus is a shape-shifter.”

Read our Cell paper, “SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms.”

Meet Jonathan