Welcome to the Abraham Lab!
We use methods in molecular virology and structural biology to study how viruses interact with cellular receptors and how neutralizing antibodies can block these interactions. We also investigate how viral polymerases replicate or transcribe viral genomes once viruses infect cells.
We focus this work on viruses that cause lethal human diseases with limited treatment or vaccine options.
Read our most recent paper, “Shifts in receptors during submergence of an encephalitic arbovirus.”
Check out our preprint on bioRxiv, “Structural and functional analysis of the Nipah virus polymerase complex.”
Read our preprint on bioRxiv, “Structural basis for VLDLR recognition by eastern equine encephalitis virus.”
Check out our paper, “VLDLR and ApoER2 are receptors for multiple alphaviruses.”
![emergingvirus4axis](http://abrahamlab.med.harvard.edu/wp-content/uploads/2020/06/emergingvirus4axis-1024x1024.jpg)
Excited to share our new study @nature led by @VirologyHarvard grad student Wanyu @wanyuviridae that explores shifted receptor usage by a unique “submerging” arbovirus, western equine encephalitis virus (WEEV).🤩 https://t.co/UnRX3CFFXy pic.twitter.com/rlUJAjIbs5
— @AbrahamLabHMS (@abrahamlabhms) July 24, 2024
So excited to be a part of this group! As a former @HHMINEWS EXROP student, then Gilliam Fellow, being selected as an investigator is a dream come true. Shout out to all @abrahamlabhms members and alumni! @HarvardMicro @BlackInMicro @HarvardMITmdphd 🤩🥳🙌🧪🥼 https://t.co/bZsMrzDjLT
— @AbrahamLabHMS (@abrahamlabhms) July 23, 2024